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Weirong Fang Selected Research

ginkgolide B

9/202110-O-(N N-Dimethylaminoethyl)-Ginkgolide B Methane-Sulfonate (XQ-1H) Ameliorates Cerebral Ischemia Via Suppressing Neuronal Apoptosis.
5/2021XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury.
3/2020Ginkgo diterpene lactones inhibit cerebral ischemia/reperfusion induced inflammatory response in astrocytes via TLR4/NF-κB pathway in rats.
10/2019XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/β-catenin signaling dependent way.
4/2018XQ-1H protects against ischemic stroke by regulating microglia polarization through PPARγ pathway in mice.
10/2011Therapeutic neuroprotective effects of ginkgolide B on cortex and basal ganglia in a rat model of transient focal ischemia.
1/2010Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia-reperfusion injury.

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Weirong Fang Research Topics

Disease

13Stroke (Strokes)
04/2022 - 10/2011
13Ischemic Stroke
12/2021 - 09/2014
12Inflammation (Inflammations)
12/2022 - 08/2015
10Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/2021 - 09/2011
9Brain Ischemia (Cerebral Ischemia)
09/2021 - 01/2010
8Infarction (Infarctions)
10/2019 - 01/2010
6Ischemia
12/2021 - 01/2010
6Reperfusion Injury
09/2021 - 01/2010
6Neoplasms (Cancer)
03/2020 - 07/2013
6Brain Edema (Cerebral Edema)
02/2020 - 01/2010
4Hypoxia (Hypoxemia)
01/2022 - 08/2009
4Pain (Aches)
01/2020 - 06/2017
3Neuroinflammatory Diseases
11/2021 - 01/2020
3Neuralgia (Stump Neuralgia)
01/2020 - 01/2018
3Hypersensitivity (Allergy)
01/2020 - 06/2017
3Thrombosis (Thrombus)
12/2015 - 01/2009
2Necrosis
11/2021 - 01/2012
2Cerebrovascular Disorders (Cerebrovascular Occlusion)
09/2021 - 03/2020
2Psoriasis (Pustulosis Palmaris et Plantaris)
10/2020 - 10/2019
2Brain Infarction
02/2020 - 10/2019
2Peripheral Nervous System Diseases (PNS Diseases)
01/2020 - 01/2018
2Cerebral Infarction
04/2018 - 11/2017
2Brain Injuries (Brain Injury)
01/2018 - 01/2016
2Hyperlipidemias (Hyperlipidemia)
10/2016 - 08/2015
2Experimental Arthritis
01/2013 - 04/2010
1Cardiovascular Diseases (Cardiovascular Disease)
09/2021
1Pheochromocytoma
09/2021
1Atherosclerosis
09/2021
1Rupture
12/2020
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2020
1Constipation
10/2020
1Autoimmune Diseases (Autoimmune Disease)
10/2020
1Sjogren's Syndrome (Sjogren Syndrome)
06/2020
1Acute Lung Injury
01/2020
1Lung Injury
01/2020

Drug/Important Bio-Agent (IBA)

12CytokinesIBA
11/2021 - 08/2015
7Neuroprotective AgentsIBA
09/2021 - 09/2011
7ginkgolide BIBA
09/2021 - 01/2010
6Pharmaceutical PreparationsIBA
09/2021 - 04/2010
5Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2019 - 01/2013
4Glucose (Dextrose)FDA LinkGeneric
12/2021 - 01/2018
4Oxygen (Dioxygen)IBA
12/2021 - 01/2018
4Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2020 - 10/2019
3Proteins (Proteins, Gene)FDA Link
12/2022 - 08/2009
3InflammasomesIBA
12/2021 - 11/2021
3Clopidogrel (Plavix)FDA Link
12/2021 - 12/2015
3GlucosidesIBA
10/2020 - 10/2019
3Therapeutic UsesIBA
10/2020 - 10/2011
3EnzymesIBA
03/2020 - 01/2009
3corydalmineIBA
01/2020 - 06/2017
3clematichinenoside ARIBA
10/2019 - 01/2016
3clematichinenosideIBA
01/2016 - 01/2013
3Thromboxane A2 (A2, Thromboxane)IBA
12/2015 - 04/2014
2Biomarkers (Surrogate Marker)IBA
04/2022 - 11/2013
2Platelet Activating FactorIBA
12/2021 - 08/2009
2Nerve Growth Factor (NGF)IBA
11/2020 - 10/2019
2ImmunosorbentsIBA
03/2020 - 01/2009
2ChemokinesIBA
01/2020 - 06/2017
2berbineIBA
01/2020 - 01/2018
2Vincristine (Oncovin)FDA LinkGeneric
01/2020 - 01/2018
2Oxycodone (Oxycontin)FDA LinkGeneric
01/2020 - 01/2018
2Chemokine ReceptorsIBA
01/2020 - 01/2018
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2019 - 10/2019
2oxiracetamIBA
01/2018 - 11/2017
2LipopolysaccharidesIBA
01/2016 - 08/2015
2Evans Blue (Blue, Evans)FDA Link
03/2014 - 01/2012
2Malondialdehyde (Propanedial)IBA
10/2013 - 09/2013
2Superoxide DismutaseIBA
10/2013 - 09/2013
2Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
09/2013 - 08/2009
2Coloring Agents (Dyes)IBA
09/2013 - 01/2012
1Dithionite (Sodium Dithionite)IBA
01/2022
1matrigelIBA
01/2022
1TicagrelorIBA
12/2021
1Phospholipids (Phosphatides)FDA LinkGeneric
12/2021
1indobufenIBA
12/2021
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
12/2021
1CaspasesIBA
11/2021
1Interleukin-18 (Interleukin 18)IBA
11/2021
1Apolipoproteins E (ApoE)IBA
09/2021
1oxidized low density lipoproteinIBA
09/2021
1LipidsIBA
09/2021
1Lipoproteins (Lipoprotein)IBA
09/2021
1Caspase 3 (Caspase-3)IBA
11/2020
1ResveratrolIBA
10/2020
1OsteopontinIBA
10/2020
1S-NitrosoglutathioneIBA
10/2020
1Purine NucleosidesIBA
10/2020
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2020
1LactonesIBA
03/2020
1DiterpenesIBA
03/2020
1ginkgolide KIBA
03/2020
1ginkgolide AIBA
03/2020
1protoporphyrin IXIBA
01/2020
1Heme Oxygenase-1IBA
01/2020
1Connexin 43 (Connexin43)IBA
01/2020
1Opioid Analgesics (Opioids)IBA
01/2020
1SuspensionsIBA
01/2020

Therapy/Procedure

9Therapeutics
12/2020 - 01/2012
3Chinese Traditional Medicine (Traditional Chinese Medicine)
09/2021 - 03/2020
3Drug Therapy (Chemotherapy)
01/2020 - 11/2013